Virus & Immunity Videos
Coordinators of the courses: B Horvat & V Volchkov
What were "Virus & Immunity" courses?
“Virus and Immunity” videos have being filmed during the courses organized at Ecole Normale Supérieure de Lyon, France, between 2005 and 2013. This was a graduate level course, within Masters Biosciences, open to French and international students. All lectures were given on English by the experts in the field (three Nobel prize laureates among lecturers in last years) and were based on the interactive approach between lecturers and students. The major goal of the course was to stimulate the originality in students and help developing their passion for the research and creative approach in the science, by guiding them through the universe of the complex interactions between the virus and the immune system.
What were "Virus & Immunity" courses about?
Viruses are the most abundant and divers pathogens on the earth, responsible for many human diseases. They have coevolved during millions of years together with the organisms they infect, by virtue of dynamic interactions, resulting in the development of host innate defences and the adaptive immune system. Course «Virus and Immunity» covers different aspects of virology and immunology and gave more insights in this dynamic interaction between different viruses and the immune system. Treated subjects included analysis of biochemical and structural aspects of the virus, variability and genetics, response to anti-viral treatment and generation of the resistance to therapy. Presented studies included the research work on several different viruses, including causative agent of AIDS in humans and of leukaemia in mice, hepatitis C virus, Infuenza, Measles virus and emergent viruses classified at the highest level of security (BSL4), including Ebola, Lassa, SARS, Nipah and Hendra viruses. Particular attention was put on the presentation of the importance of different self-defense mechanisms to eliminate infection, including dendritic cells, T and NK lymphocytes as well as mechanisms important in the control of the extent of the immune response, like T regulatory lymphocytes. Generation of T cell repertoire, immunological memory, modulation of the immune response, virus escape mechanisms, immunosuppression and viral persistence was illustrated. Finally, viral pathogenesis and anti-viral vaccination were discussed.
Filmed by chezmoiprod (2007-2009, 2011-2013) and ENSMedia (2010);
Multimedia by UNIS and ENSMedia at ENS Lyon (N Alazard-Dany, T Mahlakoiv, O Pernet, LM Bloyet, S Pilloz, G Vidal, P Sarselli, R Appourchaux)